Human-centered Design and Communities of Practice to Improve Delivery of Home-based TB Contact Investigation in Uganda (HCD-COP)

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Human-centered Design and Communities of Practice to Improve Delivery of Home-based TB Contact Investigation in Uganda (HCD-COP)

People served

People living with TB and there contacts in 10 districts of Wakiso, Mukono, Kayunga, Kiboga, Butambala, Masaka, Mityana, Mubende, Iganga and Bugiri.

Funder

National Institute of Allergy and Infectious Diseases grant R01AI104824 (JLD) 

Timeframe

January 2019 to July 2024

Status

Underway

Principal investigators

This is a study a stepped-wedge, cluster-randomized implementation trial to assess effectiveness, public health impact, and Tuberculosis (TB) diagnostic yield of a contact investigation enhanced implementation strategy compared to the usual care strategy.

The enhanced implementation strategy has two principal components:

1) an implementation facilitation package (TB education materials, a contact identification tool, a sputum collection video, and a community health rider service) targeting participant barriers to uptake and completion of TB contact investigation; and

2) a continuous quality improvement package (Community of Practice meetings, audit and feedback reports, group chat mobile application) targeting health worker barriers to implementation and maintenance.

The aim of the study is to;

1) Compare the implementation, effectiveness, and public health impact of TB contact investigation delivered via an enhanced vs. the usual delivery strategy in a stepped-wedge, cluster-randomized implementation trial.

2) Identify implementation processes and contextual factors that influence the effectiveness of the enhanced delivery strategy for TB contact investigation

3) Compare the costs and epidemiological impact of enhanced and usual-care delivery strategies for TB contact investigation.

Policy Objectives
Research Objectives